Kavli Institute NeuroLunch
Tuesday, February 9th , 2016
Rachael Dufflié PhD, Lomvardas Lab
"Translational regulation by RNA-binding protein Mex3a and Olfactory Receptor Choice"
Rachel attended the University of Virginia and majored in neuroscience and French for her undergraduate degree. She received a Fulbright fellowship to study X Chromosome inactivation in the Avner laboratory at the Pasteur Institute in Paris, France. She continued her education in France, completing a Masters and PhD at the Curie Institute exploring DNA methylation and parental imprinting in preimplantation mouse development in the Bourc’his laboratory. Rachel returned to the United States for her postdoc and works in the Lomvardas laboratory studying molecular mechanisms of Olfactory Receptor choice. She is fascinated by the principles of gene regulation that guide cells to make decisions when they are presented with multiple, equal options.
This work explores how translational regulation by RNA-binding protein Mex3a in olfactory sensory neurons may govern stochastic olfactory receptor choice. Mex3a is also expressed in several adult stem-cell types and our work may shed insight onto adult stem-cell differentiation.
Seminars are held in:
Rm. 900 Sherman Fairchild Bldg. - Note the new room location
12:00 pm - 1:00pm
1212 Amsterdam Ave.
New York, NY 10027